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Гідрогелі кардіологічного призначення на основі природних полімерів

Zuzanna Cemka1, Paweł Szarlej1, Edyta Piłat1, Przemysław Gnatowski1, Maciej Sienkiewicz1, Justyna Kucińska-Lipka1
Affiliation: 
1 Department of Polymer Technology, Faculty of Chemistry, Gdansk University of Technology, 11/12 Narutowicza St., 80-233 Gdansk, Poland s165852@student.pg.edu.pl
DOI: 
https://doi.org/10.23939/chcht16.04.564
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Abstract: 
У цій роботі описано синтез гідрогелів на основі агару та бури з додаванням і без додавання полівінілового спирту за різних концентрацій. Гідрогелі були модифіковані однаковою кількістю ацетилсаліцилової кислоти (АСК), яка має антитромботичні властивості. Проаналізовано вплив модифікації гідрогелів АСК на їхні влас-тивості.
References: 

[1] Cui, Z.; Yang, B.; Li, R.-K. Application of Biomaterials in Cardiac Repair and Regeneration. Engineering 2016, 2(1), 141-148. https://doi.org/10.1016/J.ENG.2016.01.028
[2] Piesowicz, E.; Irska, I.; Bryll, K.; Gawdzinska, K.; Bratychak, M. Poly(Butylene Terephthalate/Carbon Nanotubes Nanocomposites. Part II. Structure and Properties. Polimery 2016, 61(1), 24-30. https://doi.org/10.14314/polimery.2016.024
[3] Li, Y.; Rodrigues, J.; Tomás, H. Injectable and Biodegradable Hydrogels: Gelation, Biodegradation and Biomedical Applications. Chem. Soc. Rev. 2012, 41(6), 2193-2221. https://doi.org/10.1039/C1CS15203C
[4] Lam, M.T.; Wu, J.C. Biomaterial Applications in Cardiovascular Tissue Repair and Regeneration. Expert Rev. Cardiovasc. Ther. 2012, 10(8), 1039-1049. https://doi.org/10.1586/erc.12.99
[5] Gibas, I.; Janik, H. Review: Synthetic Polymer Hydrogels for Biomedical Applications. Chem. Chem. Technol. 2010, 4(4), 297-304. https://doi.org/10.23939/chcht04.04.297
[6] Chyzy, A.; Pawelski, D.; Vivcharenko, V.; Przekora, A.; Bratychak, M.; Astakhova, O.; Breczko, J.; Drozdzal, P.; Plonska-Brzezinska M.E. Microwave-Assisted Synthesis of Modified Glycidyl Methacrylate–Ethyl Methacrylate Oligomers, Their Physico-Chemical and Biological Characteristics. Molecules 2022, 27, 337. https://doi.org/10.3390/molecules27020337
[7] Solomko, N.; Budishevska, O.; Voronov, S. Peroxide Chitosan Derivatives and Their Application. Chem. Chem. Technol. 2007, 1(3), 137-147. https://doi.org/10.23939/chcht01.03.137
[8] Guelcher, S.A.; Gallagher, K.M.; Didier, J.E.; Klinedinst, D.B.; Doctor, J.S.; Goldstein, A.S.; Wilkes, G.L.; Beckman, E.J.; Hollinger, J.O. Synthesis of Biocompatible Segmented Polyurethanes from Aliphatic Diisocyanates and Diurea Diol Chain Extenders. Acta Biomater. 2005, 1(4), 471-484. https://doi.org/10.1016/j.actbio.2005.02.007
[9] Zubyk, H.; Mykhailiv, O.; Papathanassiou, A. N.; Sulikowski, B.; Zambrzycka-Szelewa, E.; Bratychak, M.; Plonska-Brzezinska, M.E. A Phenol-Formaldehyde Polymeric Network to Generate Organic Aerogels: Synthesis, Physicochemical Characteristics and Potential Applications. J. Mater. Chem. A 2018, 6(3), 845-852. https://doi.org/10.1039/C7TA08814K
[10] Borowska, M.; Glinka, M.; Filipowicz, N.; Terebieniec, A.; Szarlej, P.; Kot-Wasik, A.; Kucińska-Lipka, J. Polymer Biodegradable Coatings as Active Substance Release Systems for Urological Applications. Monatsh. Chem. 2019, 150(9), 1697-1702. https://doi.org/10.1007/s00706-019-02474-8
[11] Silvetti, M.S.; Drago, F.; Rava, L. Long-Term Outcome of Transvenous Bipolar Atrial Leads Implanted in Children and Young Adults with Congenital Heart Disease. Europace 2012, 14(7), 1002-1007. https://doi.org/10.1093/europace/eus024
[12] Przybytek, A.; Gubańska, I.; Kucińska-Lipka, J.; Janik, H. Polyurethanes as a Potential Medical-Grade Filament for Use in Fused Deposition Modeling 3d Printers – A Brief Review. Fibres Text. East. Eur. 2018, 26(6), 120-125. https://doi.org/10.5604/01.3001.0012.5168
[13] Szarlej, P.; Carayon, I.; Gnatowski, P.; Glinka, M.; Mroczyńska, M.; Brillowska-Dąbrowska, A.; Kucińska-Lipka, J. Composite Polyurethane-Polylactide (PUR/PLA) Flexible Filaments for 3D Fused Filament Fabrication (FFF) of Antibacterial Wound Dressings for Skin Regeneration. Materials 2021, 14(20), 6054. https://doi.org/10.3390/ma14206054
[14] McMahan, S.; Taylor, A.; Copeland, K.M.; Pan, Z.; Liao, J.; Hong, Y. Current Advances in Biodegradable Synthetic Polymer Based Cardiac Patches. J. Biomed. Mater. Res. A 2020, 108(4), 972-983. https://doi.org/10.1002/jbm.a.36874
[15] Skorokhoda, V.; Semenyuk, N.; Melnyk, J.; Suberlyak, O. Hydrogels Penetration and Sorption Properties in the Substances Release Controlled Processes. Chem. Chem. Technol. 2009, 3(2), 117-121. https://doi.org/10.23939/chcht03.02.117
[16] Wong, R.S.H.; Ashton, M.; Dodou, K. Effect of Crosslinking Agent Concentration on the Properties of Unmedicated Hydrogels. Pharmaceutics 2015, 7(3), 305-319. https://doi.org/10.3390/pharmaceutics7030305
[17] Bukhari, S.M.H.; Khan, S.; Rehanullah, M.; Ranjha, N.M. Synthesis and Characterization of Chemically Cross-Linked Acrylic Acid/Gelatin Hydrogels: Effect of pH and Composition on Swelling and Drug Release. Int. J. Polym. Sci. 2015, 2015, 187961. https://doi.org/10.1155/2015/187961
[18] Jones, L.; May, C.; Nazar, L.; Simpson, T. In Vitro Evaluation of the Dehydration Characteristics of Silicone Hydrogel and Conventional Hydrogel Contact Lens Materials. Contact Lens Anterior Eye 2002, 25(3), 147-156. https://doi.org/10.1016/S1367-0484(02)00033-4