Синтез та властивості фосфоровмісних псевдополіамінокислот поліестерного типу на основі n-похідних глутамінової кислоти

Anna Stasiuk1, Nataliia Fihurka1, Vasyl Vlizlo2, Sofiia Prychak1, Dmytro Ostapiv3, Serhii Varvarenko1, Volodymyr Samaryk1
Affiliation: 
1Lviv Polytechnic National University, 12 S. Bandery St., Lviv 79013, Ukraine 2Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, 50 Pekarska St., Lviv79010, Ukraine 3Institute of Animal Biology NAAS, 38 V. Stusa St., Lviv 79034, Ukraine anna.v.stasiuk@lpnu.ua
DOI: 
https://doi.org/10.23939/chcht16.01.051
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Abstract: 
Поліфосфоестери (ПФЕ) – це клас полімерів, що володіють високою хімічною функціональністю та здатністю до біологічного розкладання. Синтезовані нові поліфосфоестери на основі глутамінової кислоти за реакцією Стегліха. Розробленийсинтетичнийпідхіддозволяєконтролювати склад і структуру ПФЕ, а отже, їхфізичні та колоїдні властивості. Дослідження солюбілізації та цитотоксичностіinvitro довели потенціал застосування ПФЕ для доставки лікарських препаратів.
References: 

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