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Hydrogels in Biomedicine: Granular Controlled Release Systems Based on 2-Hydroxyethyl Methacrylate Copolymers. A Review

Nataliya Semenyuk1, Galyna Dudok1, Volodymyr Skorokhoda1
Affiliation: 
1 Lviv Polytechnic National University, 12 Bandery St., 79013 Lviv, Ukraine vskorohoda@yahoo.com
DOI: 
https://doi.org/10.23939/chcht18.02.143
AttachmentSize
PDF icon full_text.pdf498.38 KB
Abstract: 
The article analyzes and summarizes the latest achievements in the field of polymer systems for controlled release devices based on hydrogel materials. Possible directions of drug delivery are presented, including the use of granular hydrogels, which work on the principle of drug sorption − release in the body. The research on the synthesis regularities, structure, properties, and prospects for the use of granular hydrogels based on 2-hydroxyethyl methacrylate (HEMA) and its copolymers, in particular with polyvinylpyrrolidone (PVP), as systems for the controlled release of substances, in particular, drugs, is analyzed.
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