Synthesis and Properties of Phosphorus-Containing Pseudo-Poly(Amino Acid)sof Polyester Type Based on N-Derivatives of Glutaminic Acid
Affiliation:
1Lviv Polytechnic National University,
12 S. Bandery St., Lviv 79013, Ukraine
2Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies,
50 Pekarska St., Lviv79010, Ukraine
3Institute of Animal Biology NAAS,
38 V. Stusa St., Lviv 79034, Ukraine
anna.v.stasiuk@lpnu.ua
DOI:
https://doi.org/10.23939/chcht16.01.051
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Keywords:
Abstract:
Poly(phosphoeter)s (PPE)s are a class of polymers possessing a high chemical functionality and biodegradability. Novel, glutamic acid based poly(phosphoeter)s were synthesized by the Steglich reaction. The developed synthetic approach allows controlling the composition and the structure of PPEs, and therefore their physical and colloidal properties. The studies on solubilization and cytotoxicity in vitro proved the potential of PPEs for drug delivery applications.
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