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Electrophilic Intramolecular Cyclization of 1-(N-alkenyl)-6-methylpyrimidine-2,4-diones

Natalia Slyvka1, Yuri Gevaza2, Lesya Saliyeva1
Affiliation: 
1 Lesya Ukrainka Volyn National University, 13 Voli Ave., 43025 Lutsk, Ukraine 2 Kyiv National Trade-Economical University, 19 Kioto St., 02156 Kyiv, Ukraine natali.slyvka@ukr.net
DOI: 
https://doi.org/10.23939/chcht12.03.285
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Keywords:

Abstract: 
N-allyl(cinnamyl)substituted derivatives of 6-methyluracil were synthesized. The reactions of their bromo- and iodocyclization were performed which led to the formation of the derivatives of dihydro¬oxazolo¬pyrimidinium and dihydrooxazinepyrimidinium. The factors that favor the regioselectivity of these reactions were suggested.
References: 

[1] Sukach V., Thachuk V., Rusanov E. et al.: Tetrahedron, 2012, 68, 8408. https://doi.org/10.1016/j.tet.2012.07.099
[2] Vaskevych R., Khrypak S., Stanynets V. et al.: Ukr. Khim. Zh., 2000, 66, 47.
[3] Bentya A., Vaskevych R., Stanynets V.: Ukr. Khim. Zh., 2008, 74, 94.
[4] Gevaza Yu., Stanynets V.: Ukr. Khim. Zh., 2002, 68, 67.
[5] Kim D., Shmygarev V.: Khimiya Heterotsikl. Soed., 1995, 2, 211.
[6] Zborovskyi Yu., Orysyk V., Dobos A. et al.: Ukr. Khim. Zh., 2002, 68, 95.
[7] Slyvka N., Gevaza Yu., Stanynets V., Korolchuk S.: Ukr. Khim. Zh., 2010, 76, 102.
[8] Slyvka N., Gevaza Yu., Stanynets V.: Khimiya Heterotsikl. Soed., 2004, 5, 776.
[9] Vaskevych A., Bentya A., Staninets V.: Zh. Org. Khim., 2009, 45, 1848.
[10] Saliyeva L., Slyvka N., Vaskevych R., Vovk M.: Ukr. Khim. Zh., 2016, 82, 64.
[11] Dyachenko I., Vaskevych R., Vovk M.: Zh. Org. Khim., 2014, 50, 270.
[12] Sukach V., Thachuk V., Shoba V. et al.: Eur. J. Org. Chem., 2014, 7, 1452. https://doi.org/10.1002/ejoc.201301542
[13] Dyachenko I., Vaskevych R., Vovk M. et al.: Zh. Org. Khim., 2016, 52, 745.
[14] Shoba V., Thachuk V., Sukach V. et al.: [in:] Attanazi O., Spinelli D. (Eds.), Targets in Heterocyclic Systems: Chemitry and Properties. Vol. 17. Italian Society of Chemistry, Roma 2013, 147.
[15] Novakov I., Orlinson B., Navrotskii M.: Zh. Org. Khim., 2005, 41, 607.