Antibacterial Efficacy of Silver or Arsenic Doped Polymer Composites Against Several Kinds of Bacteria

Witold Brostow1, Marina Gahutishvili1, 2, Anthony W. Wren3, Timothy J. Keenan3, Chokchai Yatongchai3, Nathalie Hnatchuk1, Vijay Singh4
1 Laboratory of Advanced Polymers & Optimized Materials (LAPOM), Department of Materials Science and Engineering and Department of Physics, University of North Texas, 3940 North Elm Street, Denton, TX 76207, USA 2 Department of Chemistry, Ivane Javakhishvili University, 3 Ilya Chavchavadze Ave., 0179 Tbilisi, Georgia 3 Inamori School of Engineering, Alfred University, Alfred, NY, USA 4 Department of Biological Sciences, University of North Texas, Denton. TX, USA.
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Structure and several properties of AgNO3 and As2O3 doped polymer composites have been investigated, including their antibacterial activity against E. coli, S. aureus, C. albicans and S. epidermidis. New silver or arsenic doped polymer composites have been characterized by an X-ray diffraction (XRD), a scanning electron microscopy combined with an energy dispersive X-ray spectroscopy (SEM/EDS) and ion release studies. The antibacterial evaluation of each of the composite samples was conducted using S. aureus in the liquid broth culture, with 10, 20 and 30 % of liquid extract added to the bacterial culture. Control S. aureus stocks were used for comparison at each time period and were recorded at 100 % at each time period. For samples with the PLA plasticizer the bacterial viability was significantly reduced for each composition containing Ag/As and was similar for each dosage concentration.

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