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Synthesis of copper(i) chelates based on heterocyclic thioamides

Anatoliy Ranskiy1, Natalia Didenko2, Оlga Gordienko1, Таras Тіtov1,
Affiliation: 
1 Vinnytsia National Technical University, Department of Ecology, Chemistry and Environmental Protection Technologies, 95 Khmelnytske Road, Vinnytsia 21021, Ukraine 2 National Pirogov Memorial Medical University, Department of Pharmaceutical Chemistry, 56 Pirogov St., Vinnytsia 21018, Ukraine tarastitov88@gmail.com
DOI: 
https://doi.org/10.23939/chcht19.04.628
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Keywords:

Abstract: 
The paper presents modern data on the complexation of CuHal halides (Hal = Cl, Br, I; duration - 5 hours; temperature – 60-70°C) with arylamides of benzimidazole-2-thiocarboxylic acid HLI-X in alkaline aqueous-methanol solution. Such interaction forms CuLI-X chelates with a yield of 96–99% (method A), while the interaction of Cu2O (duration - 8 hours; temperature – 70-75°C) with thioamides HLI-X in methanol forms CuLI-X chelates with a yield of 90–95% (method B). The composition and structure of the new synthesized copper(I) chelates were studied by elemental analysis and IR spectroscopy. The use of copper(I) chelates as synthons in the production of biologically active compounds and new materials for technology is proposed.
References: 

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