Error message

  • Deprecated function: Unparenthesized `a ? b : c ? d : e` is deprecated. Use either `(a ? b : c) ? d : e` or `a ? b : (c ? d : e)` in include_once() (line 1439 of /home/science2016/public_html/includes/bootstrap.inc).
  • Deprecated function: Array and string offset access syntax with curly braces is deprecated in include_once() (line 3557 of /home/science2016/public_html/includes/bootstrap.inc).

Synthesis and Colloidal Properties of Polyesters Based on Glutamic Acids and Glycols of Different Nature

Sergiy Varvarenko1, Ihor Tarnavchyk1,2, Andriy Voronov2, Nataliia Fihurka1, Iryna Dron1, Nataliia Nosova1, Roman Taras1, Volodymyr Samaryk1 and Stanislav Voronov1
Affiliation: 
1Lviv Polytechnic National University, 12, Bandera str., 79013 Lviv, Ukraine; 203lab@polynet.lviv.ua 2North Dakota State University, Dept. 2760, P.O. Box 6050, Fargo, ND 58108-6050, USA
DOI: 
https://doi.org/10.23939/chcht07.02.161
AttachmentSize
PDF icon full_text.pdf211.18 KB

Keywords:

Abstract: 
The paper describes synthesis and colloidal properties of novel α-amino acid based polyesters with controllable hydrophilic-lipophillic balance. Polyesters based on glutamic acid and glycols of different nature were obtained via low-temperature activated polyesterification. Such polymers are able to form micellar structures in self-stabilized water dispersion. Peculiarities of Steglich rection in the case of polyesterefication and side processes were established and optimal conditions for polyester synthesis were determined.
References: 

[1] Jeong B., Bae Y., Lee D. et al.: Nature, 1997, 388, 860.
https://doi.org/10.1038/42218

[2] Holland S., Tighe B. and Gould P.: J. Contr. Release, 1986, 4, 155.
https://doi.org/10.1016/0168-3659(86)90001-5

[3] Jeong S. and Kim S.: Arch. Pharm. Res., 1986, 9, 63.
https://doi.org/10.1007/BF02857213

[4] Uhrich K., Cannizzaro S., Langer R. and Shakesheff K.: Chem. Rev., 1999, 99, 3181.
https://doi.org/10.1021/cr940351u

[5] Yokoyama M., Miyauchi M., Yamada N. et al.: Cancer Res., 1990, 50, 1693.

[6] Bae Y. and Kataoka K.: Adv. Drug Deliv. Rev., 2009, 6, 768.
https://doi.org/10.1016/j.addr.2009.04.016

[7] Li Y. and Kwon G.: Colloids Surf. B, 1999, 16, 217.
https://doi.org/10.1016/S0927-7765(99)00072-7

[8] Lavasanifar A., Samuel J. and Kwon G.: Adv. Drug. Deliv. Rev., 2002, 54, 169.
https://doi.org/10.1016/S0169-409X(02)00015-7

[9] Guan H., Xie Z., Zhang P. et al.: Biomacromolecules, 2005, 6, 1954.
https://doi.org/10.1021/bm0492069

[10] Puzko N., Varvarenko S., Tarnavchyk I. et al.: Visnyk Nats. Univ. "Lvivska Politechnika", 2011, 700, 364.

[11] Borzenkov M., Dolynska L., Kochubei V. et al.: Chem. & Chem. Techn., 2011, 5, 363.

[12] Lele B., Gore M. and Kulkarni M.: Synth. Commun., 1999, 29, 1727.
https://doi.org/10.1080/00397919908086160