Error message

  • Deprecated function: Unparenthesized `a ? b : c ? d : e` is deprecated. Use either `(a ? b : c) ? d : e` or `a ? b : (c ? d : e)` in include_once() (line 1439 of /home/science2016/public_html/includes/bootstrap.inc).
  • Deprecated function: Array and string offset access syntax with curly braces is deprecated in include_once() (line 3557 of /home/science2016/public_html/includes/bootstrap.inc).
  • Deprecated function: Unparenthesized `a ? b : c ? d : e` is deprecated. Use either `(a ? b : c) ? d : e` or `a ? b : (c ? d : e)` in include_once() (line 1439 of /home/science2016/public_html/includes/bootstrap.inc).
  • Deprecated function: Array and string offset access syntax with curly braces is deprecated in include_once() (line 3557 of /home/science2016/public_html/includes/bootstrap.inc).

Synthesis and Characterization of Dextran Methacrylates

Volodymyr Donchak, Ruslan Yuryev, Khrystyna Harhay and Stanislav Voronov
DOI: 
https://doi.org/10.23939/chcht08.03.303
AttachmentSize
PDF icon full_text.pdf169 KB
Abstract: 
Dextran methacrylates were received by acylation of dextran with methacryloilchloride in the presence of tertiary amines in the DMF/LiCl solution. Degree of substitution (DS) of synthesized derivatives reached 1.8 methacrylic residues per glucopyranoside unit of dextran macromolecule. Dextran methacrylates, obtained in the presence of triethylamine, with DS over 0.5 were insoluble in water. Derivatives synthesized in the presence of pyridine were separated in the form of a stable water soluble complex with pyridine chloride. These complexes maintain their water solubility up to DS = 1.8. The structurization of synthesized dextran methacrylates in water solutions initiated by redox system (NH4)2S2O8-Et3N yields active hydrogels, containing residual double bonds.
References: 

[1] Kochetkov N. and Bochkov А.: Khimiya Karbogidrativ. Khimiya, Moskwa 1967.

[2] Shalaby S., Ikada Y., Langer R. et al.: Polymers of Biological and Biomedical Significance. American Chemical Society, Washington 1994.

[3] Penzol G., Armisén P., Fernández-Lafuente R. et al.: Biotechnology and Bioengineering, 1998, 60, 518.

[4] Yasuhiko O.: Pat. US 4808709, Publ. Feb. 28, 1989.

[5] Lapenko V.: Nenasyshennye Proizvodnye Uglevodov. Izd-vo VGU, Voronezh 1986.

[6] Edman P., Ekman B. and Sjoholm I.: J. Pharm. Sci., 1980, 69, 838.

[7] Van Dijk W., Franssen O., Talsma H. et al.: Macromolecules, 1995, 28, 6317.

[8] Waysberger A., Proskauer E., Riddik J. et al.: Organicheskie Rastvoriteli. Inostrannaya literatura, Moskwa 1958.

[9] Cheronis N. and Mа Т.: Micro- i Polumicrometody Organicheskogo Funkcionalnogo Analiza. Khimiya, Moskwa 1973.

[10] Uiljams U.: Opredelenie Anionov. Khimiya, Moskwa 1982.

[11] Schehlmann V., Bauer K. and Kesselhut J.-F.: Pat. US 5739122, Publ. Apr. 14, 1998.

[12] Bauer K. and Reinhart Th.: Pat. US 5750678, Publ. May 12, 1998.

[13] Kim S., Won C. and Chu C.: Carbohydrate Polymers, 1999, 40, 183.

[14] Оаe S.: Khimiya Organicheskikh Soedineniy Sery. Khimiya, Moskwa 1975.

[15] Sanchez-Chaves M. and Arranz F.: Polymer, 1997, 38, 2501.

[16] Haynes D., Jones W. and Motherwell W.: Cryst. Eng. Comm., 2005, 7, 342.

[17] Stenekes R. and Hennink W.: Polymer, 2000, 41, 5563.

[18] Scott A.: Interpretation of the UV Spectra of Natural Products. Pergamon Press, New York 1962.