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Synthesis and Antimicrobial Activity of Products Obtained via Anionarylation of Acrylic and Metahcrylic Acids Amides and Nitriles by 5-Carboxyphenylene-1,3-Bisdiazonium Salts

Vitaliy Yatsyuk, Olena Pokryshko, Zoriana Yaniv, Galyna Tulaidan, Vitaliy Baranovskyi, Sergiy Klymnyuk and Bogdan Grishchuk
Affiliation: 
1Ternopil V. Hnatyuk National Pedagogical University 2, Kryvonosa str., 46027 Ternopil, Ukraine; baranovsky@tnpu.edu.ua 2I. Ya. Horbachevsky Ternopil State Medical University 1, Volya sq., 46001 Ternopil, Ukraine
DOI: 
https://doi.org/10.23939/chcht09.02.193
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Abstract: 
3-[3-amino(cyano)-2-chloro(bromo, thiocyanato)-(2-methyl)-3-oxopropyl]-5-chloro(bromo, thiocyanato)benzoic acids have been obtained via copper catalytic anionarylation of acrylic and methacrylic acids amides and nitriles. Their antimicrobial activity has been examined.
References: 

[1] Dombrovskii A.: Russ. Chem. Rev., 1984, 53, 943.
https://doi.org/10.1070/RC1984v053n10ABEH003133

[2] Grishchuk B., Gorbovoi P., Ganushchak N. et al.: Russ. Chem. Rev., 1994, 63, 257.
https://doi.org/10.1070/RC1994v063n03ABEH000083

[3] Grishchuk B., Gorbovyi P., Baranovskyi V. et al.: J. Org. Pharmac. Chem., 2008, 6, 16.

[4] Grishchuk B., Baranovskyi V., Klymnyuk S.: Pharmac. Rev., 2011, 4, 117.

[5] Grishchuk B., Baranovskyi V., Klymnyuk S.: Int. Sci. Conf. "Biologically Active Substances: Fundamental and Applied Problems", Ukraine, Novy Svet 2011, 36.

[6] Baranovskii V., Yatsyuk V. and Grishchuk B.: Russ. J. Gen. Chem., 2013, 83, 2040.
https://doi.org/10.1134/S1070363213110121

[7] Obushak M., Ganushchak M., Lesyuk O. et al.: Russ. J. Gen. Chem., 1997, 33, 490.

[8] Baranovskii V., Yatsyuk V. and Grishchuk B.: Russ. J. Gen. Chem., 2014, 84, 1505.
https://doi.org/10.1134/S1070363214080106

[9] Grishchuk B., Gorbovoi P., Ganushchak N. et al.: Russ. J. Gen. Chem., 1993, 63, 2335.

[10] Baranovskii V., Simchak R. and Grishchuk B.: Russ. J. Gen. Chem., 2009, 79, 269.
https://doi.org/10.1134/S1070363209020170

[11] Grishchuk B., Simchak R., Baranovskii V. et al.: Pharm. Chem. J., 2013, 47, 307.
https://doi.org/10.1007/s11094-013-0949-7

[12] Grishchuk B., Baranovskii V., Klymnyuk S. et al.: Pharm. Chem. J., 2011, 45, 532.
https://doi.org/10.1007/s11094-011-0673-0

[13] Patchornik A. and Degani Y.: J. Org. Chem., 1971, 36, 2727.
https://doi.org/10.1021/jo00817a039

[14] Degani Y. and Patchornik A.: Biochemistry, 1974, 13, 1.
https://doi.org/10.1021/bi00698a001

[15] Lundblad R.: Chemical Reagents for Protein Modification. CRC Press, Boca Raton 2014.
https://doi.org/10.1201/b16867