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Modification of Chitosan Films as a Way of their Transport Properties Regulation

Angela Murzagildina1, Elena Kulish1, Lyudmila Kuzina2, Roza Mudarisova2, Sergei Kolesov2 and Gennady Zaikov3
1 The Bashkir State University 2 The Institute of Organic Chemistry of the Ufa Scientific Centre, Russian Academy of Science 3 Institute of Biochemical Physics, Russian Academy of Sciences
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Chitosan films obtained from solutions in acetic acid and containing the antibiotics – cephazolin and cephotoxim – have been investigated and the principal possibility of regulating their transport properties as regards the medicinal preparations release has been demonstrated. This regulation can be carried out by films thermal modification consisting in heating of the formed films at the temperature of about 393 K and their treatment with sodium dodecylsulphate solution.

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