Developing a Method for Determination of Urinary Delta-Amino-Levulinic Acid using Molecularly Imprinted Polymers

Farzaneh Mollabahrami1, Abdulrahman Bahrami1, Abbas Afkhami2, Farshid Ghorbani Shahna1, Esmaeel Soleimani3
Affiliation: 
1 Excellence Centre of Occupational Health, Occupational Health and Safety Research Center, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran 2 Department of Analytical Chemistry, Bu-Ali Sina University, Hamadan, Iran 3 Department of Occupational Health Engineering, School of Health, Shiraz University of Medical Science, Shiraz, Iran bahrami@umsha.ac.ir
DOI: 
https://doi.org/10.23939/chcht14.03.334
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Abstract: 
Delta-amino-levulinic acid (ALA) has been introduced as a biological exposure index for workers exposed to lead. In this study, a new analytical method has been developed using molecularly imprinted polymers (MIPs) in microextraction by packed sorbent for urine samples. A spectrophotometric analysis was carried out for urine samples. Fourier transform infrared spectroscopy was used to determine the main constituents of MIPs. The optimized method was fast, sensitive, selective, easy to use and friendly to the environment. The results indicated that the developed method is a suitable and rapid method for the bio-monitoring of individuals exposed to lead.
References: 

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